The Ratio of SEP70 to Pepsin as a Biomarker of Laryngopharyngeal Reflux
نویسندگان
چکیده
منابع مشابه
Sensitive pepsin immunoassay for detection of laryngopharyngeal reflux.
OBJECTIVES/HYPOTHESIS To determine whether measurement of pepsin in throat sputum by immunoassay could be used as a sensitive and reliable method for detecting laryngopharyngeal reflux (LPR) compared with 24-hour double-probe (esophageal and pharyngeal) pH monitoring. STUDY DESIGN Patients with clinical LPR undergoing pH monitoring provided throat sputum samples during the reflux-testing peri...
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15 صفحه اولSignificance of the pepsin from the saliva in the diagnosis and treatment of laryngopharyngeal reflux disease.
Etiopathogenesis of the laryngopharyngeal reflux has not been sufficiently clarified. It is believed that damage to the lining of laryngopharynx in laryngopharyngeal disease occurs in the use of acid and pepsin. The diagnosis of reflux acidic 24-hour Dual probe pH-metry is considered the gold standard. However, since the laryngopharyngeal reflux is often non-acidic new diagnostic methods are be...
متن کاملPepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease.
OBJECTIVES/HYPOTHESIS The objective was to investigate the potential use of pepsin and carbonic anhydrase isoenzyme III (CA-III) as diagnostic markers for laryngopharyngeal reflux disease. STUDY DESIGN Prospective cell biological investigation was conducted of laryngeal biopsy specimens taken from 9 patients with laryngopharyngeal reflux disease and 12 normal control subjects using antibodies...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2018
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2018.06.029